Different DNA Structures Nucleate the Folding of Proteins to form specific complexes that modulate the readout of ...

Archaeal motility structures, comprising specialised appendages such as archaella and type IV pili-like filaments, are pivotal for cellular movement, adhesion and intercellular communication. These ...

Artificial intelligence (AI) is transforming how scientists understand proteins—these are working molecules that drive nearly every process in the human body, from cell growth and immune defense to ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...

Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their blueprint—the genetic information. Here, the basic building blocks of proteins, ...

They build our bodies and orchestrate the molecular processes in cells that keep them healthy. They also present a wealth of targets for new medications. From everyday pain relievers to sophisticated ...

Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on the resolved structure of the NiV polymerase L-P ...

Google DeepMind's groundbreaking new AI predicts not only the structure of proteins, ligands, DNA, RNA and "all of life's molecules," but how they'll interact. It promises a radical, revolutionary ...

A new computer process makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process could revolutionize drug ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...