Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

“If you have a machine—for example, a bike—all the different components of the bike would need to be fit in the right places for them to function,” said Lambda Moses, a computational biologist at ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

This eBook cuts through the complexity of spatial techniques, featuring a series of interviews with pioneers in the field, and peer-reviewed research from the Taylor & Francis journal portfolio. This ...

From startups to giants in pharma and tools, the use of spatial biology is growing in importance in drug discovery. LatchBio, a four-year-old San Francisco builder of software and data infrastructure ...